We produce sensitive and specific tools for making discoveries in next generation sequencing data through the use of statistical modeling. Our tools are used by members of academia, medicine, and industry alike.

Software developed in the Salzman lab:

KNIFE (Known and Novel Isoform Explorer) detects linear and circular RNA isoforms both at annotated and unannotated boundaries. Publication, Github

MACHETE (Mismatched Alignment CHimera Tracking Engine) detects gene fusions at annotated splicing boundaries. Publication, Github